In other matches in the Champions Chellenge hockey tournament, New Zealand beat England while Argentina beat Japan.
FC Goa fought back from a goal down to hold defending champions Atletico de Kolkata 1-1 in their second round match of the Indian Super League at the Nehru stadium, in Fatorda, Goa, on Wednesday.
But for third-placed Spurs, who trail leaders Manchester City and Liverpool by five points, this may prove to be a loss that leaves them with too much ground to make up.
Emotions ran high as Nantes paid tribute to their former player Emiliano Sala on Wednesday in their first game since the Argentine went missing in a light aircraft over the English Channel.
The win took second-placed Real to 62 points after 29 games, two behind champions Barca who beat Leganes 2-0 on Tuesday.
Manchester United beat Aston Villa 3-1 to maintain their six-point Premier League lead.
Images from Saturday's action in the Premier League.
Paris St Germain extended their Ligue 1 lead to 13 points with a 4-3 home victory against Girondins de Bordeaux on Sunday but the French champions were again exposed at the back and had Neymar sent off. A Marquinhos double, Edinson Cavani's 200th PSG goal and a goal by Kylian Mbappe put the capital side on 65 points from 26 games but they lost captain Thiago Silva to a muscle injury and Neymar picked up a straight red card for a late challenge in stoppage time.
In the other matches of the day, Olympic champions Australia began their quest in style, scoring an authoritative 4-1 win over former winners Germany while Spain beat India 2-1.
Germany outclassed last edition silver medallist Netherlands
India's Virat Kohli continued to torment New Zealand with the bat, hitting an unbeaten 85 to secure a six-wicket victory with nearly 17 overs to spare in the first One-day International at Dharamsala on Sunday.
Gokulam Kerala were crowned champions of the Hero Indian Women's League after a dramatic 3-2 victory over Kangchup Road Young Physical and Sports Association (KRYPHSA) FC in the final
Manchester City survived a stirring Leicester City fightback to claim a 2-1 win that lifted them above Liverpool into third in the Premier League on Saturday.
Olympique de Marseille will lead Ligue 1 into the two-week break thanks to Michy Batshuayi's half-volleyed winner in a 2-1 home victory over Lille on Sunday.
Arjun Atwal returned the day's best card of six-under 66 to leap to the tied 19th spot after the penultimate round of the $ 500,000 Henrico County Open on the Nationwide Tour in Richmond.
The drag flick ace scored a hat-trick as Pakistan beat India 3-2 in the Azlan Shah hockey tournament.
The British Open will end on a Monday for the first time since the late Seve Ballesteros won at Royal Lytham in 1988 after high winds caused havoc on Saturday.
Images from football action around European leagues played on Sunday
Two-time champion and top seed Saina Nehwal and P V Sindhu reached the pre-quarterfinals of the $ 120,000 Swiss Open Grand Prix Gold in Basel.
With two tough stages in the Pyrenees up next, five times champion Lance Armstrong and the other favourites took it easy.\n\n
Images from the English Premier League match played between Manchester City and Newcastle on Wednesday
IMAGES from the English Premier League matches played on Wednesday
Sanjeev Rajput was the highest placed Indian at the 13th position in the ISSF World Cup.
Imperious Liverpool extended their Premier League home winning streak against Arsenal to six on Saturday with an easy 4-0 victory that lifted them to second in the table.
A summary of Saturday's matches in the Premier League.
News of all that's transpired on and off the football field
Delhi Waveriders showed no mercy on the Kalinga Lancers as they inflicted a humiliating 5-0 defeat on the Odisha-based side in match seven of the Hero Hockey India League (HHIL) in New Delhi.
Images from the first One-Day International between India and England, in Pune, on Tuesday.
David Silva scored a late goal as runaway leaders Manchester City won their 13th successive Premier League game and restored their eight-point lead with a 2-1 victory against West Ham United on Sunday.
India lost 0-1 to Spain, while South Korea thrashed England 5-1 on the opening day of the Rabo Bank eight-nation hockey tournament
City were not at their all-action best early on as Burnley looked comfortable at the back, but the game turned on a penalty decision that incensed the visitors when Bernardo Silva was adjudged to have been brought down by Burnley goalkeeper Nick Pope just before the half hour.
Former Real youth player Joselu pulled a goal back for Alaves in the 59th minute, powering in a header from a free kick, but Benzema rounded off the victory for second-placed Real with an exquisite solo run and goal in the 70th minute.
Philippe Coutinho scored his first league goal since returning to Barcelona to help his side draw 1-1 at home to an excellent Sevilla side in La Liga on Sunday.
With nine more rounds still remaining in this marathon 23-round tournament Ganguly took his tally to 11 points out of a possible 14.
Summary of sports events and persons who made news on Tuesday.
Olympiakos coach taken to hospital, match abandoned after crowd trouble
Hetmyer smacked three sixes and eight fours in his entertaining knock, helping his side chase down a modest target of 128.
IMAGES from the English Premier League matches played on Sunday
Misbah had the dubious honour of becoming the first player from his country to finish on 99 not out during their first innings of last week's seven-wicket first test victory in Jamaica.